perform correlative studies on pre-treatment tumor biopsy specimens analyses will include the assessment of immunohistochemical expression patterns (germinal center B cell vs.assess the ability to collect stem cells from patients treated with salvage VIPER who then undergo autologous stem cell transplantation.assess conversion of chemo-resistant to chemo-sensitive disease.assess event free survival and overall survival.The secondary objectives of this study are to: VIPER) to patients with relapsed or refractory diffuse large B-cell non-Hodgkin's lymphoma determine the complete and partial response rates and the toxicity profile of bortezomib (VELCADE, formerly PS-341) when administered in combination with DICE chemotherapy plus rituximab (i.e.The primary objective of this study is to: Why Should I Register and Submit Results?.
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